8 mo baby with regression of motor skills, can no longer sit or roll over, startles easily with loud noises, macrocephaly, bright red fovea centralis, decreased peripheral vision. Diagnosis, deficiency, and accumulation of?
a) Tay-Sachs disease, Hexosaminidase A deficiency, GM2 ganglioside
b) Niemann-Pick disease, Acid sphingomyelinase deficiency, Sphingomyelin
c) Hurler syndrome, Alpha-L-iduronidase deficiency, Dermatan sulfate
d) Krabbe disease, Galactocerebrosidase deficiency, Galactocerebroside