__ pancreatitis is characterized by progressive, permanent damage to ___, resulting in the impaired secretion of ___ and ___; up to -% of ___ pancreatitis cases are associated with excessive ___; other risk factors include ___ and repeated episodes of ___.
a) Acute; pancreas; insulin; glucagon; 70-90%; acute; alcohol; trauma
b) Chronic; pancreas; insulin; glucagon; 20-30%; chronic; caffeine; infection
c) Acute; liver; bile; lipase; 50-60%; chronic; smoking; inflammation
d) Chronic; liver; bile; lipase; 10-20%; acute; alcohol; pancreatitis