Starlee8759 Starlee8759 10-03-2024 Medicine contestada How to administer Activase? 0.9mg/kg (max 90mg). FIRST, Bolus 10% of total dose over 1 minute. THEN, infuse the rest over 60 minutes. NOTE: Activase must be use within 8 hours after recinstitued. Activase must be infuse by itself.