The main difference between mammalian and reptilian teeth is that reptiles are usually homodont while mammals are typically heterodont. This means that all reptiles’ teeth are the same shape and on the other hand, mammals have different types of teeth, like incisors, canines, premolars, and molars. The advantage of mammalian teeth is in those difference in size and shape of teeth which results in their different function. Thus, mammalians are more efficient and specialized for different types of feeding.