D
Essentially, the path begins from the nucleus where the DNA is transcribed by RNA polymerase that makes a nascent mRNA.
Explanation:
The nascent mRNA is processed into a mature mRNA that is sent to ribosomes that outline the membrane of the Rough Endoplasmic Reticulum. When a polypeptide chain is translated by the ribosome, from the mRNA, the chain enters the lumen of the RER where it finds chaperons that help the proper folding of the chain into a required secondary, tertiary or quaternary structure. The protein undergoes further post-translational modification. Quality Control also happens here and only ‘well-made’ proteins are allowed to pass down to the Golgi apparatus. The Golgi apparatus also performs a few additional post-translation modifications but its major role is tagging these proteins for delivery, and packaging them. Vesicle budding off of this organelle carries the proteins to the cell membrane. The vesicle fuses with the cell membrane enabling the contents in the vesicle to be emptied outside the cell.
Learn More:
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