Respuesta :
Answer:
f: Cartilage model develops
b: Cartilage calcifies and a bone collar forms
a: Ossification center forms in the diaphysis
c: Ossification centers form in the epiphyses
e: Epiphyseal plates ossify
d: Bone replaces cartilage
Explanation:
Endochondral ossification follows these steps.
(a) Mesenchymal cells differentiate into chondrocytes which develops a cartilage model of the future bony skeleton.
(b) Blood vessels on the edge of the cartilage model bring osteoblasts that forms a bony collar.
(c) Capillaries penetrate cartilage and deposit bone inside cartilage model, forming primary ossification center. Ossification center that forms in the diaphysis, the center of the bone, and is the source of bone development
(d) Cartilage and chondrocytes continue to grow at ends of the bone while medullary cavity expands and remodels. Ossification centers form in the epiphyses or the end points of the bones
(e) Secondary ossification centers develop after birth. Epiphyseal plates ossify
(f) Bone replaces cartilage
The chronological order of the steps of endochondral ossification is the cartilage developed with calcified and bone collar. Diaphysis formed followed by epiphyses. The plates in epiphyses ossify with the bone replacement.
What is endochondral ossification?
The process of the longitudinal development of the bone with the replacement with bone is termed as endochondral ossification.
The process is initiated with the differentiation of mesenchymal cells into chondrocytes that results in the development of cartilage model.
The developed cells, started the appearance of blood vessels that forms the bone collar.
The capillary network found to proliferate within the center of the cartilage and forms the center of bone development that is diaphysis.
The formation of diaphysis follows the development of the cavity, and the epiphysis at the end of bone develops.
The epiphysis plates develop after the birth as secondary ossification.
The birth resulted with the replacement of cartilages with bones.
Thus, the correct sequence of the endochondral ossification is f, b, a, c, e, and d.
Learn more about endochondral ossification, here:
https://brainly.com/question/11129176
