Some restriction enzymes cut at specific and unambiguous sequences (e.g., NotI at GCGGCCGC). As such, the distance between two such sites in a large random DNA sequence is 48, assuming a 50% G+C DNA content.However, the sequence recognized by XhoII is said to be ambiguous (Pu-GATC-Py, where Pu = any purine and Py any pyrimidine). What, therefore, is the expected distance between two XhoII sites in a large random sequence? A) 4 × 4 × 4 × 4B) 1 × 4 × 4 × 4 × 4 × 1C) 2 × 4 × 4 × 4 × 4 × 2D) 46E) 42 × 22