There are three main checkpoints in the cell cycle. Each checkpoint serves a different purpose and have their certain cyclins present. At the G1 checkpoint, a cell undergoes certain conditions to see if it is prepared for cell division. If a cell receives restrictions from the G1 checkpoint and can not continue into the next phase, what could the cell do next? A) All cells pass the G1 checkpoint and enter into the next phase. B) The cell can enter the G0 (resting stage) until conditions can improve. C) The cell will always go directly into the G2 checkpoint to continue the cell cycle. D) The cell will directly enter the M phase and all of the errors will be fixed during this phase.

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Answer:

B) The cell can enter the G0 (resting stage) until conditions can improve.

Explanation:

The problem needs to be fixed before we can continue to other phases which is why the cell has check points.

In case if the cell receives restrictions from the G1 checkpoint and cannot continue into the next phase, then the cell can enter the resting stage or G0 stage until conditions can improve.  

• The surveillance mechanisms, which monitor the integrity, order, and fidelity of the prime events of the cell cycle are known as cell cycle checkpoints.  

• The cell cycle is monitored at three checkpoints, that is, the G1 checkpoint, the G2 checkpoint, and the M checkpoint.  

• The G1 checkpoint takes into consideration that whether all the conditions are suitable for the cell division to advance.  

• In the G1 checkpoint, the cell, which does not qualify all the requirements, will not be permitted to advance into the S phase.  

• The cell in such a case will halt the cycle and will try to resolve the issue, or it can be said that the cell will move into Go or quiescent stage.  

• At the Go stage, the cell will wait for the further signals till the conditions get better.  

Thus, if the cell receives restrictions in the G1 checkpoint then the cell will move into the Go stage and will wait for further signals. The correct statement is option B.

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