Select all of the following that can be used to describe the structure of enzymes, the importance of the shape, and the relationship of enzyme shape and function.

a. Amino acids are linked by hydrogen bonds with various chemical groups attached to give enzymes their two dimensional shape.
b. Amino acids are linked by hydrogen bonds with various chemical groups attached to give enzymes their three dimensional shape.
c. Amino acids are linked by hydrogen bonds with various chemical groups attached to give enzymes their four dimensional shape.
d. Amino acids are linked by peptide bonds with hydrogen bonds between nearby amino and carboxyl groups to give enzymes their two dimensional shape.
e. Amino acids are linked by peptide bonds with interactions between the side groups of amino acids to give enzymes their three dimensional shape.
f. Amino acids are linked by peptide bonds with interactions between the side Amino acids are linked by peptide bonds with various chemical groups attached to give enzymes their four dimensional shape.
g. One or more polypeptide chains are folded and bond together in the fourth level of protein organization.
h. The shape of an enzyme determines its function The number of amino acids in an enzyme determines its function.
i. The active site binds with the substrate Enzymes are substrate specific.
j. Alteration of active sites does not alter the enzymatic reaction.

The proteins are one of the most important components of the living body. These proteins are formed of the monomers called amino acids. These amino acids are polymerisation in a two dimensional structure by means of peptide bond. This is the bond between the amino group of the preceding group with the carboxylic group of the succeeding group. This structure is called the primary structure. The primary structure then undergoes several intermolecular bonding with the side groups via covalent bonds, hydrogen bonds, disulphide bonds etc which forms the secondary structure which is the 3d structure.

The active site of the enzymes are formed by a particular structure of amino acids which are complementary to that of the substrate. So with the alteration of that site, the enzyme cannot act any more. Thus the enzyme becomes non functional.