During the process of translation, which component has the responsibility of ensuring that the tRNA is correctly charged, i.e. carries the amino acid that corresponds to its anti-codon? During the process of translation, which component has the responsibility of ensuring that the tRNA is correctly charged, i.e. carries the amino acid that corresponds to its anti-codon? the peptidyl transferase center of the ribosome the messenger RNA the decoding center of the ribosome the aminoacyl-tRNA synthetase the peptidyl-tRNA Request Answer

Before an amino acid can be incorporated into the growing polypeptide chain in the ribosomes, they must first recognize and be attached to a their cognate tRNAs through a process called tRNA charging/loading. This process also called aminoacylation is aided by the aminoacyl tRNA synthetases also called tRNA ligases. Failure of the enzymes to carry out the correct charging are determined resulting in cellular dysfunctions. The process occurs in 2 steps

1. The enzymes binds ATP to the amino acid to form a complex of amino acid-AMP.

2. The amino acid is then linked with tRNA and the AMP is released this the tRNA is "charged" and ready to function