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An Rh-negative mother presents to the local emergency department in active labor. She reports having received no prenatal care and cannot recall having received any post-partum intervention following her first pregnancy. The mother reports that she believes the father of both children is Rh positive. The newborn exam reveals marked anemia. Which type of hypersensitivity reaction has likely occurred in the child in-utero that has led to the development of anemia?
a. Type II
b. Type IV
c. Type III
d. Type I

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ayfat23

Answer:

a) type II

Explanation:

Type II hypersensitivity reffers to the situation where there is the host tissues is damaged as a result of the cellular lysis which is induced by the direct binding of antibodies to surface of the antigen cells Type II hypersensitivity is associated with antibodies of( immunoglobulin) . Its main Target is the membrane-associated antigens. During the phase of sensitisation, antibodies are produced which helps in recognition of substance or metabolites which is accumulated in cellular membrane structures. type II reactions are caused by some factors medications such as;

1)hydrochlorothiazide

2)penicillins

type II hypersensitivity also play a role in cellular destruction through autoantibodies

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