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Answer:
There is an important relationship among homeostasis, defective mitochondria, and the symptoms caused by LHON.
Explanation:
There is a great relationship among homeostasis, defective mitochondria and the symptoms caused by LHON because defective mitochondria disturbs the homeostasis in the body. If mitochondria works properly, homeostasis will be maintained whereas if there is any defect occurs in the mitochondria then the whole homeostasis will be adversely affected because mitochondria is the powerhouse of the cell responsible for the production of energy for the cell. Symptoms occurs due to Leber's hereditary optic neuropathy (LHON) also effected the state of equilibrium in the body.
The relationship among homeostasis, defective mitochondria and the symptoms caused by LHON is the following:
The power center of the cell, the mitochondria are also involved in homeostasis, the maintenance of a stable internal environment even in the face of variations in the external environment.
Mitochondrial diseases can be caused by inherited mutations in mitochondrial DNA or defects in the proteins responsible for regulating mitochondrial division, affecting the body's homeostasis.
- Leber's Hereditary Optic Neuropathy (LHON) is the first disease associated with a mutation in the mitochondrial genome, specifically it produces the specific degradation of neurons involved in sending information from the eye to the brain (RGC).
- This disease is caused almost entirely by three mutations in mitochondrial DNA (mtDNA).
- The first symptoms are blurred vision, with unilateral or bilateral onset, which over time affects and / or worsens in both eyes, with loss of visual acuity and color vision.
- Vision loss is painless and is caused by degeneration of the optic nerve, specifically of the retinal ganglion cells (RGC).
Therefore, we can conclude that LHON is a disease associated with a mutation in the mitochondrial genome affecting the body's homeostasis.
Learn more here: https://brainly.com/question/18296870
