Lipids are hydrophobic because they do not mix with water. Lipids are made of long chains of carbon and hydrogen. ... The partial charges on the water molecule cannot interact with the neutral lipid molecule and thus water and lipids do not mix.
"this hydrophobic ("water fearing") nature of lipids is driven by the bonds between these many carbons and hydrogens. ... Thus, long chains of carbon-hydrogens bonds form a nonpolar molecule."
