Researchers identify a gene in cockroaches that is responsible for their ability of nerve regeneration. How might it be possible for this gene to be used in treating human paralysis?

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This gene could be analyzed to determine its homology level with a human gene, which then could be restored in its normal expression. This strategy can restore the normal phenotype in defective human cells.

Sequence homology, which refers to the level of evolutionary relationship among genetic or proteins sequences, is a fundamental subject matter to determine gene function.

From this approach (sequence homology search), researchers can identify valuable genes involved in diseases in which the restoration of their normal expression levels can be used to restore the normal phenotype in defective cells.

In this case, the identification of a gene in cockroaches that is responsible for nerve regeneration could be used for subsequent identification of a human homologous gene sequence, which then can be restored in order to treat human paralysis.

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