The transcription factor that binds directly to the tata-box sequence is TFIID. This transcription factor (TFIID) is a macromolecular protein complex.
The TATA box is a fundamental nucleotide gene sequence that forms the eukaryotic core promoters, which are required to initiate transcription.
TFIID is a macromolecular protein complex (also called the RNA polymerase II preinitiation complex), which acts as a general transcription factor during the initiation of eukaryotic transcription.
TFIID recognizes and binds to the TATA box (core promoter) and also binds with different activator and repressor proteins in order to regulate the transcriptional activity.
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