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Answer:
The Anti-Federalists opposed the ratification of the 1787 U.S. Constitution because they feared that the new national government would be too powerful and thus threaten individual liberties, given the absence of a bill of rights.
Although Hamilton held deep reservations about the new government, he signed the Constitution because he felt that it met his basic requirements for a central government. Hamilton also knew that in order for the fledgling United States to survive, this new government had to be approved.