The missing number in the sequence is 52.
In order to determine the missing number, the pattern in the sequence has to be determined.
The difference between the second and first number is 144 - 127 = 17
The third number is 3 times smaller than the second number: 144 / 48 = 3
The difference between the fourth number and the third number is 66 - 48 = 18.
The fifth number is 2 times smaller than the fourth number: 66/33 = 2
Based on this sequence, the sixth number would be 19 more than the fifth number. 33 + 19 = 52
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