Developing and characterizing a retinal explant culture system will help to facilitate investigation of novel methods of improving retinal stem cell therapy.
Transplantation of stem cells and progenitor cells to treat neurodegenerative diseases of the central nervous system (CNS) is currently a subject of intense scientific investigation.
Studies state that these cellular grafts may also be beneficial for treating sight-threatening conditions including macular degeneration, retinitis pigmentosa, and glaucoma by increased neuroprotection and regeneration.
Retinal explants prepared using culturing in the B27/N2 medium system can be a useful in vitro model for investigating methods of enhancing retinal stem cell therapy.
The development of specific techniques to enhance the efficacy of cell transplantation could be facilitated by this kind of model systems that are quick, efficient, and easily manipulated.
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