Respuesta :
S-Nitrosothiols serve as a good source of nitric oxide ((*)NO) mainly due to the ease of cleavage of the S-N bond which consequently produces (*)NO. The reductive decomposition of S-nitrosoglutathione (GSNO) by l-ascorbic acid (vitamin C) yields (*)NO which was monitored both electrochemically (using NO-probe) and spectrophotometrically.
What is S-nitrosoglutathione, or GSNO?
A source of bioavailable nitric oxide (NO), S-nitrosoglutathione (GSNO) is an endogenous S-nitrosothiol (SNO) that is essential for nitric oxide (NO) signaling. SNOs, which act as endogenous NO carriers and donors, coexist with NO in cells.
Does GSNO develop when glutathione reacts with nitric oxide (NO)?
According to some data, glutathione can react with both exogenous and endogenous NO produced by nitric oxide synthases to create GSNO.
Is GSNO a nitric oxide reserve?
According to reports, S-Nitrosothiols like GSNO are essential to the chemical biology and physiological functions of nitric oxide (NO). GSNO has been described in numerous ways, such as a NO storage or as a crucial element of NO-dependent signal transduction.
What is Ascorbic Acid?
Vitamin C is also known as ascorbic acid. Cosmetics and personal care products may also contain ascorbic acid salts such calcium ascorbate, magnesium ascorbate, sodium ascorbate, and sodium ascorbyl phosphate.Vitamin C is also known as ascorbic acid. Cosmetics and personal care products may also contain ascorbic acid salts such calcium ascorbate, magnesium ascorbate, sodium ascorbate, and sodium ascorbyl phosphate.
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