A ratio of the dose of the drug that is toxic to humans versus the minimum effective dose for that pathogen is assessed to predict the potential for toxic drug reactions. This is called the therapeutic index (TI).
- A ratio that contrasts the blood level at which a medication becomes toxic and the level at which it is effective. The safer a medicine is, the higher its therapeutic index (TI).
- The dosage needed to produce the desired therapeutic response divided by the dose that causes toxicity is known as the dos-to-dose ratio.
- Utilizing the 50% dose-response points, including TD50 (toxic dosage) and ED50, is a typical technique for determining the TI (effective dose).
- The dosage range or blood plasma or serum concentration often anticipated to have the intended therapeutic effect is known as a drug's therapeutic range.
- This does not imply that patients won't benefit from doses below the minimal threshold or won't have negative effects if doses are kept within
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