Calcium channel blockers are specific medications that are used to lower blood pressure. They prevent calcium from entering the cells of the heart and arteries.
Calcium is responsible for the contraction of heart and arteries more strongly .In contrast Calcium channel blockers allow blood vessels to relax and open. Muscle contraction is mostly dependent upon influx of calcium, its scarcity causes relaxation, particularly in arterial beds. The major effects of the calcium channel blockers are relaxation of vascular and arterial smooth muscle cells resulting in arterial vasodilation.
Some examples of calcium channel blockers include Norvasc (amlodipine) Plendil (felodipine) and DynaCirc (isradipine). Oral magnesium acts as a natural calcium channel blocker, increases nitric oxide, improves endothelial dysfunction, and induces direct and indirect vasodilation.
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