Appasamy M, Jauniaux E, Serhal P, et al. Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation.

Respuesta :

A biological system's capacity to detoxify these reactive products and the creation and buildup of oxygen reactive species (ROS) in cells and tissues create an imbalance that results in oxidative stress.

How oxidative stress (OS) causes infertility?

  • According to the study, OS affects the granulosa cells of the ovary's ability to produce steroid hormones, particularly E2 levels, a key indicator of ovarian response.
  • FSH and E2 are frequently utilized as predictive tests for ovarian reserve on day three.
  • It has become more common to forecast ovarian reserve using sensitive immunoassays for protein hormones released by granulosa cells, such as inhibin B and AMH.
  • Higher levels of follicular phase AMH are related with good ovarian response, whereas higher levels of follicular phase FSH and lower levels of inhibin B are associated with poor ovarian response.
  • The success of IVF is less likely when basal E2 levels are higher in the follicular phase.
  • Early follicular recruitment following the early luteal surge of FSH as a result of the failing follicle cohort and less inhibin B could be the reason of this.
  • These results imply that these hormones have a significant impact on ovarian responsiveness to stimulation and the effectiveness of IVF treatments.

Learn more about the Oxidative stress with the help of the given link:

https://brainly.com/question/1383848

#SPJ4