The breakdown products of isoleucine are succinyl-CoA and acetyl-CoA. This amino acid would be classified as both glycogenic & ketogenic.
Isoleucine (Ile or I) is one of the 20 amino acids generally found in proteins. Isoleucine is an essential amino acid and contains two functional groups i.e. a carboxyl group (COOH) and an amine group (NH2).
It has the following side chain: CH(CH3)CH2CH3, therefore, it is a branched chain, non-polar, hydrophobic amino acid.
The catabolism of Isoleucine begins in the muscle and produces NADH and FADH2 which can be used for ATP formation. Since isoleucine catabolism concludes with the production of acetyl-CoA and succinyl-CoA, hence, it is both glycogenic and ketogenic.
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