Respuesta :
De novo pathway and salvage pathway are the two pathways through which nucleotides are synthesized. While the salvage system makes nucleotides from preexisting bases and nucleosides, the de novo pathway does so using small molecules.
What distinguishes the nucleotide pathways of de novo and salvage?
De novo synthesis: From simpler precursor substances, nucleotides are created. Preformed bases are retrieved and connected to active riboses via salvage mechanisms.
What is the purine biosynthesis salvage pathway?
Free adenine is converted into AMP by the enzyme adenine phosphoribosyl transferase (APRT). The purine base in IMP, hypoxanthine, and guanine both undergo a similar reaction when catalyzed by the enzyme hypoxanthine-guanine phosphoribosyl transferase (HGPRT).
What is purine nucleotide de novo synthesis?
The intriguing process of creating purines from scratch involves adding the atoms that make up the purine ring to ribose-5-phosphate one at a time. As a result, purines are created directly as nucleotide derivatives by assembling the atoms that make up the purine ring system on the ribose.
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