Brefeldin a is a drug that disrupts transport from the er to the golgi apparatus. what other organelles and membranes are immediately (in the short term) affected?

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12-09-2022
Social Studies

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Brefeldin a is a drug that disrupts transport from the er to the golgi apparatus. what other organelles and membranes are immediately (in the short term) affected?

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khuranashilpa76 khuranashilpa76 · Answer 1 · 2022-09-16T21:14:31+02:00

Brefeldin is a drug that disrupts transport from the er to the Golgi apparatus. And other organelles and membranes are Lysosomes, transport vesicles, plasma membranes, and nuclear membranes.

This cellular organelle is primarily responsible for the transport, modification, and packaging of proteins and lipids to specific target sites. The Golgi apparatus is located in the cytoplasm of cells and is present in both plant and animal cells. Mitochondria and peroxisomes are central organelles in regulating cellular redox balance and homeostasis.

Properly folded and assembled proteins in the ER are packaged into COPII-coated transport vesicles that flank the ER membrane. Shortly thereafter, the sheath sheds, and the vesicles fuse to form tubular clusters of vesicles that migrate to the Golgi apparatus on the microtubule pathway. The Golgi apparatus is often found in close proximity to the ER within the cell.

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