Respuesta :
The probability that the first child of Clara and Charles will be a boy with hemophilia is 1/4.
How to calculate the probability?
It shouldbe noted the dominant and recessive alleles is given as H and h. It should be noted that A and a also represent the tyrosinase alleles.
The father of Clara had hemophilia.
Therefore, the probability that the first child of Clara and Charles will be a boy with hemophilia will be:
= 1/2 × 1/2
= 1/4.
Therefore, the probability is 1/4.
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In humans, hemophilia (OMIM 306700) is an X-linked recessive disorder. The dominant and recessive alleles represented by H and h . Albinism is an autosomal recessive condition . A and a represent the tyrosinase alleles. A healthy woman named Clara (II-2), whose father (I-1) has hemophilia and whose brother (II-1) has albinism, is married to a healthy man named Charles (II-3), whose parents are healthy. Charles's brother (II-5) has hemophilia, and his sister (II-4) has albinism. The pedigree is shown.
Determine the probability that the first child of clara and charles will be a boy with hemophilia.
