in addition to epinephrine, your body also releases a steroid that responds to stress. epinephrine wears off quickly, but the steroid, corticosterone, can last hours. where we would predict that corticosterone (the signaling molecule) would bind to its receptor?

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12-10-2022
Biology

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in addition to epinephrine, your body also releases a steroid that responds to stress. epinephrine wears off quickly, but the steroid, corticosterone, can last hours. where we would predict that corticosterone (the signaling molecule) would bind to its receptor?

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jaiswalsaurabh45609 jaiswalsaurabh45609 · Answer 1 · 2022-10-15T17:08:16+02:00

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

By interacting with mineralocorticoid and glucocorticoid receptors in the brain, corticosteroid hormones help the body adapt to stress (MR and GR). These receptors serve as important transcription factors in considerable part.

The glucocorticoid receptor controls how the body will react to stress, even though cortisol is a blatant indicator that stress is there. A mechanism that affects the production of specific stress-response proteins is activated when cortisol binds to the glucocorticoid receptor.

To learn more about glucocorticoid receptor follow this link

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