Imagine that a toxin is introduced to the body and inhibits the establishment of the proton gradient in the intermembrane space as a result, ATP synthase would be unable to produce ATP. The correct answer is option(e).
The production of ATP by ATP synthase is dependent on the proton gradient in the intermembrane gap. As a result, the toxin will render it inert. In this situation, oxidative phosphorylation rather than substrate-level phosphorylation is now suppressed.
Pyruvate is a glycolysis byproduct that won't be harmed by a toxin. It is anticipated that the toxin will prevent NADH from being oxidized because it is crucial in creating a proton gradient. The proton gradient is created by the protons created during NADH to NAD+ conversion. NADH is unlikely to be oxidized if the gradient is missing.
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The complete question is:
Imagine that a toxin is introduced to the body and inhibits the establishment of the proton gradient in the intermembrane space. What would you predict would be the result?
a. NADH would be oxidized
b. Fermentation could not occur
c. Substrate-level phosphorylation would be inhibited
d. Pyruvate would be unable to enter the Citric acid cycle
e. ATP synthase would be unable to produce ATP