which option is an insoluble substance? responses the substance takes a long time to dissolve in the solvent. the substance takes a long time to dissolve in the solvent. all of the substance will dissolve in the solvent. all of the substance will dissolve in the sol, vent. about 100 g of the substance will dissolve in 100 ml of solvent. about 100 g of the substance will dissolve in 100 ml of solvent. little or none of the substance will dissolve in the solvent.