Respuesta :
Genetics. Schizophrenia runs in families, although no single gene is known to be to blame. It's more likely that distinct gene combinations render people more susceptible to the illness.
Only a few genes have been proven to be associated to schizophrenia. A mutation in the SETD1A gene clearly increases the risk of the disease. Other genetic variants linked to schizophrenia have minor impacts, whereas a single mutant copy of SETD1A is linked to a significant increase in disease risk.
Deletions or duplications of genetic material in any of several chromosomes, which might influence several genes, are also likely to raise schizophrenia risk. A minor loss (microdeletion) in a region of chromosome 22 known as 22q11 may be involved in a small percentage of cases.
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