The resting plasma membrane would become more potential inside-positive as more Na+ ions leak into the cell and fewer K+ ions leak out, resulting in a net increase in the Na+ ion concentration in the cell.
A difference in voltage across the plasma membrane is produced by the selectivity of Na+ and K+ channels in the presence of concentration gradients. This voltage difference is essential for a number of biological processes, such as nerve concentration , muscle cell contraction, hormone secretion, and the regulation of osmotic concentration . The action potential's repolarization phase would be most impacted by blocking the sodium inactivation mechanism. The resting potential would remain unchanged. The action potential would merely have a longer duration than usual as the only effect.
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