Aspartate aminotransferase (ast) and alanine aminotransferase (alt) are liver enzymes and shows liver function.
Aspartate aminotransferase is a component of the malate-aspartate shuttle in the heart and is also involved in the production of neurotransmitters and the neuro-glial pathway in the brain, as well as gluconeogenesis in the liver, kidney, and adipose tissue.
The enzyme alanine aminotransferase (ALT) is mostly present in liver cells. It is also present in heart and muscle cells in addition to the liver. Alanine is converted by ALT into pyruvate for use in cellular energy production.
The liver, brain, pancreas, heart, kidneys, lungs, and skeletal muscles all contain AST. The liver is the major location of ALT. If your AST levels are excessive, it may indicate damage to tissues other than the liver. You may have a liver if you have high ALT levels.
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