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The doctor prescribed 100 mg, available is 1,000 mcg/0.5 ml. 50 ml should be administered to the patient.

Based on the patient's known weight and the anticipated adult dose of the medication, Clark's formula is an algorithm used to determine the appropriate dosage for pediatric patients. The following example illustrates the Clark's rule equation, which states that the adult dosage of a drug multiplied by the patient's weight in pounds divided by the typical standard weight of 150 pounds (68 kg) equals the pediatric dosage:

(Weight* divided by 150 lbs.) x Adult Dose** = Pediatric Dosage

(Weight*** divided by 68 kg) x Adult Dose** = Pediatric Dosage

One of the well-known pediatric drug dosing rules that takes into account the patient's weight is Clark's rule, which is mentioned in the medical literature. Salisbury's rule, Penna's rule, and the Body Surface Area rule are further formulae that use pediatric weight to determine drug dosage. Young's rule, Webster's rule, and Fried's rule are further approaches to Clark's rule that also take into account pediatric age to determine radiopharmaceutical medicine dosages used in nuclear imaging.

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