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peripheral blood mononuclear cells (pbmcs) and bone marrow samples are isolated from a patient, and then analyzed using flow cytometry. Leukemia, SCID, and CGD disorders could be diagnosed using this technique.
A type of blood malignancies known as leukemia generally start in the bone marrow and are characterized by abnormally high blood cell production. Blasts or leukemia cells are the terms used to describe these immature blood cells. An elevated risk of infections, bone discomfort, fatigue, bleeding, and bruising are a few of the warning signs. The absence of healthy blood cells is what makes this illness distinct. Blood testing and bone marrow biopsies are frequently used in the diagnosis procedure. Leukemia's exact origin is not known. Both genetic and environmental (non-inherited) variables are thought to be involved. Smoking, ionizing radiation, petrochemicals (including benzene), previous chemotherapy, and Down syndrome are risk factors. People with a family history of the illness form another category.
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