The blood-brain barrier is a highly selective semi-permeable membrane or border of endothelial cells. It is important for the protection from pathogens and toxins.
The substances that cannot pass the blood-brain barrier are:
- The blood-brain barrier is found in most of the blood vessels surrounding the brain. Its primary function is to protect the brain from circulating toxins and drugs.
- The blood-brain barrier follows several mechanisms for the crossing of solutes, molecules, and other substances. The mechanisms like endocytosis, saturable transporters, and extracellular pathways.
- Water, oxygen, and glucose can easily be diffused through the barrier. The low-fat molecules are not easily passed through the barrier.
Thus, the molecules with high electric charge and fat molecules are not passed through the barrier.
To know more about the blood-brain barrier, refer to the following link:
https://brainly.com/question/9035919
