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Gene expression in eukaryotes can be regulated at various levels. Certain mutations in flies may cause them to develop an extra set of legs or wings. _______, which determine the formation and arrangement of body parts in multicellular organisms, control gene expression by regulation of ________. the options for the first answer are A. Small interefering RNA B. operons C. Hox genes and for the second answer the answers are pre-mRNA splicing B. mRNA degradation or C. DNA transcription