Sympathetic dominance---
Increase in muscle mass----- Raise
Decreased in insulin----- Lower the tmr
Decrease in TSH ---- Lower the tmr
Increase in adrenal cortex function ------raising the tmr
Increase in thyroxine ---- raising the tmr
Training for a marathon -----raising the tmr
Malabsorption of nutrients-------- Lower the tmr
Decrease in adrenal medulla function ------ Lower the tmr
Epinephrine secretion------- raising the tmr
The total metabolic rate is the total energy used by the body each day. Physical activity such as Training for a marathon require more energy and leads to increasing the tmr. Whereas, malabsorption of nutrients lowering the tmr because less food is being supplied, and therefore less energy production.