Option C. A mutation affecting checkpoint 3 proteins that prevent attachment of spindle fibers damage. describes a mutation that would lead to an increase in the frequency of nondisjunction.
The detachment of the homologous chromosomes relies upon the get-together of the chromosomes at the metaphase plate in the tropical district, when each chromosome is connected with its comparing axle fiber. Spindle assembled checkpoint (SAC) is the assembly of specific proteins that check to see if the spindle fibers are properly attached to the chromosome or not. proteins that are connected to checkpoint 3.
these proteins investigate whether the arrangement of the shafts with every chromosome is correct, and afterward flag the metaphase to anaphase progress. This causes the development of the chromosome towards the post.
Any change to SAC causes expulsion of this designated spot, and chance emerges that shaft fiber can not append the chromosomes appropriately and there is the unusual development of the chromosome causing non-disjunction.
Any mutation in the checkpoint 2 protein enables the production of defective DNA, which can then proceed to the subsequent phase of the cell cycle. The second type of defective DNA results in point mutations at the nucleotide level and is not associated with non-disjunction because it does not deal with the chromosome arrangement within the cell.
know more about nondisjunction here: https://brainly.com/question/29746177
#SPJ4
(complete question)
image attached
